The first was William Henry Harrison (1841), whose presidency was the shortest in history thanks to his inaugural speech being the longest: he delivered it in the rain and caught pneumonia.
Zachary Taylor (1850) caught lethal cholera from cherries washed in dirty water. Disease also claimed Warren G Harding (1921) and Franklin Delano Roosevelt (1945) with a stroke and cerebral haemorrhage, respectively.
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The other four: JFK (1963), Abraham Lincoln (1865), William McKinley (1901) and James Garfield (1881) were all killed by an assassin’s bullet, though Garfield technically survived the attack only to catch blood poisoning from his surgeon’s unsterilized scalpel.